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Neuroscientist & CEO @ Mobio Interactive. I support my team in the pursuit of effective and accessible healthcare for every human.

In three previous stories, I summarised what Ray Dalio’s book Principles attempts to achieve, reviewed the concepts that resonated most strongly with me, and argued that emphasis on personality profiling within companies is misplaced, and besides, carries clear risks for the employee, organisation and society that are often overlooked, minimised or otherwise misunderstood.

Here, in my final installment, I settle in on my own area of expertise: neuroscience. Prior to focusing 100% of my time at Mobio Interactive, I was a Principal Investigator of Neuroscience at the Zurich Psychiatric Hospital. …


After publishing two other Medium stories on Ray Dalio’s book Principles — the first summarising the book’s contents and aim, and the second delving into its most salient contemplations — it’s now time to get a little more critical.

In particular, I’d like to challenge Dalio’s reliance on and recommendation of personality profiling.

Dalio is such a strong believer in the power of personality profiling that he implemented de facto baseball cards for every individual at Bridgewater.

The underlying premise is simple and valid: no one is good at everything. Therefore, any reasonably complex project can be better executed when…


This overview of Principles’s most salient concepts describes everything you need to know about Dalio’s meritocracy manual, if you aim to contribute to a successful organisation (as, in one way or another, I hope we all do).

Previously, I provided a terse overview of the book and its author. This deeper dive selects and explores nine specific concepts from Principles that I found particularly profound, and at times, provocative.

1. Pain & Struggling Well. For anyone interested in self-help, self-improvement, and self-actualisation, Dalio’s ideas on pain, failure, and suffering are worth taking the time to contemplate and meaningfully internalise. …


In my quest to transition from Principal Investigator neuroscientist to CEO neuroscientist, I have been guided by the frank criticism and advice of numerous mentors. Naturally, book recommendations have arisen, including billionaire hedge fund manager Ray Dalio’s meritocracy manual, Principles.

After reading a couple of books on the goal-setting framework known as “ORK”, I picked up Principles to further my research into organisational strategy, and proceeded to devour it cover to cover. Despite Dalio’s instruction to treat the third part of the book as quick reference only, I pored over every word on every page. Principles became the appetiser, side…


It’s early morning at RebelBio, the SOSV biotech accelerator nested in the basement of a futuristic glass tower at Imperial College London. Soon I’ll be given a tour of the facilities by its Associate Director, but in the meantime I’m chilling on a semicircular blue cotton couch in a surprisingly modest atrium. With this welcomed spare time, I turn the last few pages of a legendary series of letters written two millennia ago.

“Letters from a Stoic” by Lucius Annaeus Seneca was introduced to me by @richardrobinson during a Chinaccelerator event in Beijing back when my company, Mobio Interactive (MI)…


Right now, people all over the world are sharing insights on their mental wellbeing through the clinically-validated app, Am Mindfulness (or simply “Am”). Am may be the world’s most rigorously examined mindfulness app and this clinical validity helps it stand out in a crowded “digital mindfulness” marketplace. As Chief Scientist of Mobio Interactive, the creators of Am, I have inside access to this wealth of anonymous data — a fascinating position to be in for any neuroscientist.

For example, I know on what day of the week people around the world experience the most fatigue (surprise, it’s Friday!). I also…

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